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Ashwagandha Side Effects: Is It Safe? (The Truth)

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Ashwagandha Side Effects: Is It Safe? (The Truth)

The Truth About Ashwagandha Side Effects: Are You at Risk?

If you're feeling stressed or anxious, you might have considered ashwagandha as a natural remedy, but do you know its potential side effects? Don't worry; we've got your back! 

In this blog post, we'll dive into the potential side effects of ashwagandha, its benefits, and how to use it safely. So, let's get to the 'root' of the matter and uncover the truth about ashwagandha’s side effects.

Key takeaways:

  • Ashwagandha offers stress reduction and immune support.
  • Side effects may include gastrointestinal issues, sleepiness, blood pressure or sugar changes, and more.
  • Consult your healthcare provider before using ashwagandha.
  • Pregnant or breastfeeding women should avoid it.
  • Cycle ashwagandha for best results and minimal long-term side effects.

What is Ashwagandha?

Ashwagandha, scientifically known as Withania somnifera, is a small evergreen shrub native to India, North Africa, and the Middle East. It has been used for thousands of years to promote overall health and wellness in Ayurvedic medicine, a traditional Indian holistic healing system.

Ashwagandha is classified as an adaptogen, which helps the body manage and adapt to stress by supporting the adrenal glands and balancing stress hormones. In addition, the plant's roots are also used to make various supplements, such as capsules, powders, and tinctures.

Research suggests that ashwagandha may help reduce anxiety and stress, improve sleep, enhance cognitive function, and support immune health. Furthermore, it may have anti-inflammatory and antioxidant properties, which contribute to overall health and wellness.

What are some side effects of ashwagandha?

Below are some of the most common side effects of ashwagandha.

1. Digestive issues

Ashwagandha, known for its numerous benefits, can sometimes lead to digestive problems. Users may experience stomach discomfort, diarrhea, or nausea. A study conducted on 75 participants found that 6.7% of the individuals reported digestive issues after consuming ashwagandha root extract for 60 days. To avoid these side effects, starting with a lower dose and gradually increasing it is essential, allowing your body to adjust.

2. Sleepiness and drowsiness

Some people experience sleepiness or drowsiness as a side effect of ashwagandha, which could be attributed to its calming properties. A small percentage of users (3.3%) reported drowsiness in an 8-week study with 64 participants(1). While this effect might benefit individuals struggling with insomnia, it could be inconvenient for others. Therefore, be cautious when driving or operating heavy machinery if you experience drowsiness after taking ashwagandha.

3. Headaches

Although ashwagandha is considered safe for most people, a few may experience headaches as a side effect. Therefore, monitoring your body's response and adjusting the dosage is essential. If headaches persist, consider consulting a healthcare professional for personalized advice.

4. Allergic reactions

Some individuals may have an allergic reaction to ashwagandha. Symptoms can include skin rash, itching, or difficulty breathing. If you experience these signs, discontinue use immediately and consult a healthcare professional.

5. Lower blood pressure

Ashwagandha has been observed to lower blood pressure in some cases. For example, a study with 98 participants showed a significant reduction in systolic and diastolic blood pressure after eight weeks of ashwagandha supplementation. However, while this could benefit those with high blood pressure, it might pose risks for people who already have low blood pressure or are on medication for hypertension.

6. Liver toxicity

Although rare, there have been reports of liver toxicity associated with ashwagandha use. In a case study, a 32-year-old woman developed liver injury after consuming ashwagandha supplements for six weeks. If you have a history of liver problems or are taking medications that can affect the liver, consult your healthcare provider before using ashwagandha.

7. Interactions with thyroid medications

Ashwagandha may increase thyroid hormone levels, making it potentially problematic for individuals with thyroid issues or those taking thyroid medications. For example, a study found that ashwagandha supplementation increased T4 levels, which could lead to thyrotoxicosis in predisposed individuals. Therefore, it's essential to consult a healthcare professional if you have a thyroid condition or are on thyroid medications before using ashwagandha.

8. Pregnancy and breastfeeding concerns

Ashwagandha is not recommended for pregnant or breastfeeding women, as its safety during these periods is not well-established. Animal studies have suggested potential adverse effects on fetal development. To ensure the health and safety of both mother and baby, it's best to avoid ashwagandha during pregnancy and breastfeeding.

9 Interactions with antidepressants

Ashwagandha may interact with antidepressant medications, leading to increased drowsiness or other side effects. If you're taking antidepressants, consult your healthcare provider before adding ashwagandha.

10 Fertility concerns for men

While ashwagandha has been associated with improved male fertility, excessive intake may have the opposite effect. A study on 180 infertile men showed that ashwagandha supplementation significantly improved sperm quality and fertility. However, it's crucial to stick to the recommended dosage and avoid overconsumption, as excessive amounts could potentially lead to adverse effects on fertility. Always consult a healthcare professional before starting any supplement regimen, especially if you have fertility concerns.

Are there any long-term side effects of ashwagandha use?

While ashwagandha is generally considered safe for most people, there is limited research on its long-term side effects. As a result, most studies on ashwagandha have been conducted over relatively short durations, usually ranging from a few weeks to a few months.

In the studies conducted, ashwagandha has demonstrated a good safety profile with no significant long-term side effects reported. For instance, a 2009 study involving 75 participants taking ashwagandha root extract for 60 days showed no serious adverse effects(2).

However, it's essential to approach long-term use with caution. Some potential concerns regarding long-term ashwagandha supplementation include the possibility of developing tolerance or experiencing unknown side effects over longer periods of time. Also, the long-term safety of ashwagandha in certain populations, such as pregnant or breastfeeding women, is not well-established.

How can VitaRx's personalized approach help you benefit from ashwagandha while minimizing side effects?

VitaRx is dedicated to providing personalized vitamin packs catering to your health and wellness goals. Take our brief health assessment to receive tailored recommendations on vitamins and supplements, including ashwagandha, based on your unique needs. By doing so, you'll be guided toward the right dosage and complementary nutrients that will optimize the positive effects of ashwagandha.

VitaRx's commitment to quality and transparency ensures you receive the highest quality ashwagandha supplement. All products are tested by advanced private laboratories and manufactured following the FDA's Good Manufacturing Practices (cGMPs). In addition, with their focus on allergen and diet-conscious products, you can trust that the ashwagandha supplement provided by VitaRx aligns with your lifestyle and dietary preferences.

As your health needs change, you can easily customize your subscription with VitaRx. For example, if you find ashwagandha particularly beneficial or need to adjust your intake due to side effects, you can do so without any contracts or commitments.

Experience the benefits of ashwagandha with VitaRx's personalized approach. Take the health assessment today, and embark on a journey towards improved well-being with the convenience and expertise offered by VitaRx.

Frequently asked questions (FAQ)

Can ashwagandha interact with other medications or supplements?

Ashwagandha may interact with certain medications, such as sedatives, anticonvulsants, blood thinners, and blood pressure medications. This is not an exhaustive list. Therefore, you must consult your healthcare professional before starting ashwagandha supplementation if you are on any medications or have existing health conditions. 

Is ashwagandha safe for pregnant or breastfeeding women?

Although ashwagandha has been used traditionally in Ayurvedic medicine, there is limited research on its safety during pregnancy and breastfeeding. Due to the lack of conclusive evidence, avoiding ashwagandha supplementation during pregnancy and breastfeeding is recommended. Instead, consult your healthcare provider for personalized advice.

Can I take ashwagandha daily, or should I cycle it?

While the short-term daily use of ashwagandha is safe and effective in several studies, the long-term effects still need to be well established. Therefore, as a precaution, some experts recommend cycling ashwagandha—taking it for a few weeks or months (up to 3 months) and then taking a break. Consult with a healthcare professional to determine the best approach for your needs.


As we reach the end of our exploration into the side effects of ashwagandha, it's essential to remember that this ancient herb has numerous potential benefits. Still, just like anything else, moderation is key. So before starting ashwagandha supplementation, consult your healthcare provider and responsibly embrace this adaptogenic herb's power.

And as you embark on your journey with ashwagandha, don't forget to take it with a grain of laughter—because laughter is the best medicine, right? So, next time you're stressed, think of ashwagandha as your stress-busting superhero, always there to help you adapt and conquer. Here's to a healthier, happier, and more "a-adapt-o-genic" you!

Key takeaways

  • Ashwagandha is an adaptogenic herb with numerous benefits, including stress reduction and immune support.
  • Possible side effects include gastrointestinal issues, sleepiness, and lowered blood pressure or blood sugar levels.
  • Always consult your healthcare provider before starting ashwagandha supplementation, especially if you have existing health conditions or take medications.
  • Pregnant or breastfeeding women should avoid ashwagandha due to limited research on its safety.
  • Consider cycling ashwagandha to ensure the best results and minimize potential long-term side effects.
  • When used responsibly, ashwagandha can be a powerful tool for improving health and well-being.


  1. A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults
  2. Efficacy of Withania somnifera on seminal plasma metabolites of infertile males: a proton NMR study at 800 MHz
  3. (PDF) A Standardized Withania Somnifera Extract Significantly Reduces Stress-Related Parameters in Chronically Stressed Humans: A Double-Blind, Randomized, Placebo-Controlled Study 
  4. Ashwagandha as a Unique Cause of Thyrotoxicosis Presenting With Supraventricular Tachycardia - PMC 

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