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Last update: February 4, 2025

4 minute read

Do Probiotics Expire?

Do probiotics expire? Learn how their potency changes over time, signs they’ve gone bad, and the best ways to store them for maximum effectiveness.

Derick Rodriguez

By Derick Rodriguez, Associate Editor

Edited by Yerain Abreu, M.S.

Learn more about our editorial standards
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Ever stumbled upon an old bottle of probiotics tucked away in your fridge and wondered if they're still effective? You're not alone.

The world of probiotics can be confusing, especially when it comes to understanding their shelf life and potency.

Let's dive deep into what happens to probiotics as they age and how you may maximize their benefits.

Key takeaways

  • Probiotics do expire, and their effectiveness diminishes after the expiration date
  • Proper storage, like refrigeration, may extend the shelf life of probiotics
  • Viable cell counts decrease over time, even under ideal conditions

    Understanding the shelf life of probiotics

    Probiotics are live bacteria and yeasts that support your gut health. But like all living organisms, they have a lifespan.

    Once the expiration date passes, the number of viable microorganisms in your supplement may drop significantly.

    The number of viable cells, measured in colony-forming units (CFUs), indicates the potency of the probiotic. Higher CFUs generally mean more beneficial bacteria, which may contribute to better gut health.

    A study evaluating 33 expired probiotic products found that while 22 products still contained viable microorganisms, the total cell counts were mostly below the effective dose recommended by the manufacturers.

    Only 5 products were within or above the original claimed cell count. This means that even if some bacteria are still alive, there might not be enough to provide the health benefits you're expecting.

    If you're interested in learning more about the benefits of probiotics, check out this detailed guide.

    VitaRx Tip

    Always follow the storage instructions on the label to maintain their effectiveness. If you're curious about probiotics for women and specific storage needs, this resource offers valuable insights.

    Packaging and storage conditions

    How you store your probiotics plays a crucial role in their longevity. Probiotics are sensitive to factors like temperature, moisture, and light. Proper packaging and storage conditions may help maintain their viability longer.

    For example, vacuum-packaged probiotic instant coffee stored at 4°C (39°F) maintained cell viability above (10^7) log CFU/g for about 726 days (approximately 2 years).

    However, the same product stored at higher temperatures like 30°C (86°F) and 37°C (98.6°F) showed a significant decrease in viability.

    Key factors affecting probiotic shelf life:

    • Temperature: Cooler temperatures slow down the metabolism of probiotics, helping them last longer.
    • Packaging: Vacuum-sealed or airtight containers protect against moisture and oxygen, which may harm probiotics.
    • Light exposure: UV light may damage probiotics, so opaque or amber-colored bottles are preferable.

    Do all probiotics require refrigeration?

    Not all probiotics need refrigeration, but many do. Some shelf-stable probiotics are designed to withstand room temperatures.

    Health made easy: your go-to resource for essential vitamins and supplements

    The relationship between probiotics and gut health

    Maintaining a healthy gut microbiome is crucial for overall well-being. Probiotics play a significant role in:

    • Supporting digestion.
    • Enhancing immune function.
    • Improving mental health.

    If you're exploring how probiotics may aid in weight loss and gut health maintenance, this article provides comprehensive information.

    Fun fact

    Did you know that probiotics are being studied for use in space travel? Maintaining astronauts' gut health on long missions is crucial, and probiotics may play a significant role in keeping them healthy far from Earth.

    Dos and don'ts of storing probiotics

    Do’s

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      Do store probiotics in the refrigerator if recommended.

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      Do keep them in their original packaging to protect from light and moisture.

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      Do check the expiration date before use.

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      Do follow the manufacturer's instructions for optimal storage conditions.

    Don’ts

    • icon

      Don't store probiotics in the bathroom where humidity is high.

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      Don't leave them in direct sunlight or near heat sources.

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      Don't transfer them to unsealed containers.

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      Don't ignore storage instructions, assuming all probiotics are the same.

    Frequently asked questions (FAQ)

    Here are some of the most frequently asked questions about the shelf life of probiotics.

    Final thoughts

    Probiotics may be a fantastic addition to your wellness routine, but it's important to be mindful of their expiration dates and storage conditions.

    When in doubt, don't hesitate to reach out to a healthcare professional for advice on choosing and using probiotics effectively.

    Remember, maintaining a healthy gut is a key component of overall well-being. Whether through supplements or diet, supporting your microbiome is a step toward a healthier you.

    Sources and references


    Editor

    Derick Rodriguez avatar

    Derick Rodriguez focuses on editing health and wellness-related content. With over half a decade of experience in the digital realm, Derick has developed a unique skill set that bridges the gap between complex health concepts and accessible, user-friendly communication. His approach is deeply rooted in leveraging personal experiences and insights to illuminate the nuances of health and wellness topics, making them more approachable and empowering readers with knowledge and confidence.

    Editor

    Yerain Abreu avatar

    Yerain Abreu is a content strategist with over seven years of experience. He earned a Master's degree in digital marketing from Zicklin School of Business. He focuses on medical and health-related content, working with top healthcare professionals to ensure content is engaging and reliable.

    At VitaRx, we're not just passionate about our work — we take immense pride in it. Our dedicated team of writers diligently follows strict editorial standards, ensuring that every piece of content we publish is accurate, current, and highly valuable. We don't just strive for quality; we aim for excellence.


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